Lyme Disease Protocols

This protocol was put together by Dr. Nicola drawing on a number of information sources as well as her own clinical experience. The actual remedies selected, as well as testing done to assess underlying stressors on the body, will vary according to the individual.  Please do not take this as medical advice. This protocol is for educational purposes only. Work with your own doctor, or make an appointment with Dr. Nicola, to have a full evaluation and an individually tailored program designed for you.

Areas to address
Working with Lyme disease there are many areas that must be addressed.  Typical antibiotic regimens may miss many of these areas, so if antibiotic therapy has been initiated, it will be most effective if combined with integrative regimens such as this.

Some of the areas to cover include:

  • Primary infections – Bb spirochete
  • Co-infections – Erlichia and Babesia
  • GI infections – parasites, mycoplasma
  • Viral infections – herpes, Coxsackie, influenza, Echo viruses, measles
  • Yeast overgroth – candidiasis
  • Heavy metal toxicity
  • Mold toxicity
  • Immune dysfunction
  • Systemic inflammation



Antimicrobials -
Dr. Nicola’s Lyme Support Formula
Contains: Cat’s Claw (Uncaria tomentosa), Lignan-vitae (Guaiacum officinale), Astragalus (Astragalus membranceus), Andrographis (Andrographis paniculata).
Dose: 5-10 drops twice daily.

Dr. Nicola’s Fresh Teasel Root
A high quality teasel extract helpful in the treatment of Lyme and other tick-borne illnesses.
Contains: Teasel Root (Dipascus sylvestris)
Dose: 5 drops twice daily.

Dr. Nicola’s Anti-Parasite Formula
A potent blend of herbs to support the body in ridding parasites, amoeba and helminths (worms). Artemesia is often used in the treatment of Babesia, a common co-infection of Lyme disease.
Contains: Wormwood (Artemesia absinthium), Sweet Annie (Artemisia annua), Garlic (Allium sativum), Epasote (Chenopodium ambrosoides), Yellow Gentian (Gentiana lutea), Goldenseal (Hydrastis canadensis), Black Walnut (Juglans nigra), Oregon Grape Root (Majonia aquifolium), Quassia bark (Quassia amargo), Pau D’Arco (Tabebuia impetiginosa), Tansy (Tanacetum vulgare), Ginger (Zingiber officinalis), Clove (Syzygium aromaticum).
Dose: 60 drops 3 times daily.

Dr. Nicola’s Anti-Fungal Formula
Good for combating yeast overgrowth, combines will with anti-parasite formula to promote balanced intestinal flora.
Contains: Garlic (Allium sativum), Curlycup gumweed (Grindelia squarrosa), Oregon Grape (Mahonia aquifolium), Wild Bergamot (Monarda fistulosa), Pau D’Arco (Tabebuia heptaphylla), Eastern Arborvitae (Thuja occidentalis), Cinnamon (Cinnamomium cassia), Fennel (Foeniculum vulgare).
Dose: 60 drops three times daily.


Detoxification & Methylation Support -
Dr. Nicola’s Smilax
Smilax glabrae helps to neutralize endotoxins and is helpful for relieving pain and helping with herxheimer reactions.
Contains: Chinese Sarsaparilla (Smilax glabrae).
Dose: 1-2 dropper(s)ful twice daily.

Dr. Nicola’s Detox Support Formula #1
A low-alcohol blend of liver cleansers and tonifiers.
Contains: Astragalus (Astragalus membranaceous), Burdock (Arctium lappa), Dandelion root (Taraxacum officinale), Goji Berry (Lycium chinensis), Lemon Balm (Melissa officinalis), Milk thistle (Silybum marianum), Wu-Wei-Zi fruit (Schisandra chinensis), Thorowax (Bupleurum falcatum), Oregon Grape Root (Mahonia aquifolium), Licorice root (Glycyrrhiza glabra).
Dose: 60 drops two to four times daily.

Dr. Nicola’s Detox Support Formula #2
A low-alcohol blend of liver cleansers and tonifiers. This formula does not contain milk thistle, which makes it appropriate for use by individuals taking Mepron or Malarone.
Contains: Astragalus (Astragalus membranaceous), Burdock (Arctium lappa), Dandelion root (Taraxacum officinale), Goji Berry (Lycium chinensis), Lemon Balm (Melissa officinalis), Wu-Wei-Zi fruit (Schisandra chinensis), Thorowax (Bupleurum falcatum), Oregon Grape Root (Mahonia aquifolium), Licorice root (Glycyrrhiza glabra).
Dose: 60 drops two to four times daily.

Readisorb Liposomal Glutathione
Neuroprotective and antioxidant, helps cognitive function and energy.

Methylcobalamin (Methyl-B12) (compounding pharmacy)
1-2 mL injected IM 3-4x weekly
Provides energy boost, immune support and gentle detox by boosting methylation pathways.


Immune Support -
Transfer Factor Multi-Immune (Researched Nutritionals) – 2 caps before bed
Transfer Factor LymPlus (Researched Nutritionals) – 1-2 caps daily
Andrographis Plus (Metagenics) – 1 three times daily


Digestive Support -
Ultra Flora Plus DF (Metagenics) – 1-2 daily
Prescript-Assist Pro (Researched Nutritionals) – 1-2 daily


Neurological Health/ Inflammation
EPA/ DHA Extra Strength (Metagenics) – 2-4 gelcaps daily.
Enteric coated source of high potency omega-3’s to support the nervous system and reduce inflammation.
InflammaQuell (Researched Nutritionals)-  3 caps twice daily between meals.
100% Vegetarian, Buffered Proteolytic Enzyme Formula


Pain/ Mood/ Sleep Support -
Dr. Nicola’s Sleep Support Formula
Gentle and nourishing sedative and nerve-calming herbs to help promote restful and consistent sleep.
Contains: Milky Wild Oats (Avena fatua), California Poppy (Eschoscholzia californica), Catnip (Nepeta cararia), Passionflower (Passiflora incarnata), Yan Hu Suo (Corydalis hanhusuo).
Dose: 1-2 teaspoons ½ hour before bed, up to 4 times per night, not to exceed 3 teaspoons per night.

Dr Nicola’s Nerve Pain Formula
Herbs that are specifically tailored to reduce neurological inflammation and pain, and nourish the nervous system.
Contains: Fresh tumeric (Curcuma longa), St John’s Wort (Hypericum perforatum), Lemon Balm (Melissa officinalis), Jamaican Dogwood (Piscidia erthythrina), Skullcap (Scutellaria lateriflora), Blue Vervain (Verbena hastata).
Dose: 60 drops every two hours for 1-2 days, then 2-4 times a day as needed.


Digestive Support -
RestorProbiotic – 1 scoop at night, at least 2 hours after last dose of antimicrobial herbs/ antibiotics.


Summary of the Protocol

  • Transfer Factor Multi Immune: 2 caps at night
  • Transfer Factor Lym-Plus: 1-2 caps daily
  • Dr. Nicola’s Lyme Support Formula: 5 drops three times daily
  • Dr. Nicola’s Fresh Teasel Root: 5 drops three times daily
  • Nerve Pain Formula: 30-60 drops twice daily
  • Soothe and Relaxx: 2 caps three times daily
  • RibosEnergy: 1 scoop twice daily
  • RestorProbiotic: 1 scoop mixed in water before bed



Other treatments to consider:
Hyperbaric Oxygen Therapy: 60 min sessions, twice daily, 5 days per week for 30-60 sessions.
BodiHealth/ Jai machine
Chelation therapy for heavy metal detox:
Kelatox (EDTA suppository) – 1 suppository every night in conjunction with glutathione suppositories.
DMSA – 100mg every third night.

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